In buying a used vehicle, is over 100K miles the kiss of death?

the gmc yukon is a good dependable vehicle any thing with 100,000 miles is going to have issues, and usually between 115, and 145000 the stock tranny goes bad, depends on what towing the vehicle did. So as long as you budget for an expensive fix on any vehicle over 100,000 then you are going to be more realistic about things. There are a lot of high mileage vehicles out there, save your money, and keep your eye out, look for a one owner private party deal, that is the best way and cheapest way to get a decent truck, stop looking at dealers, they are all overpriced. be ready, pay cash put the money in the bank, instead of always owing something.